Here’s the description from the History Channel web site:
The line that separates male from female is blurred. In India, the Hijra are a two-thousand-year-old religious sect; their ranks filled with boys who have been–or desire to be–castrated. We meet a Hijra who’s in love with a married man, and who fears that she’ll soon be abandoned and forced into a life of prostitution. In Maine, a male English Professor changed his name to Jennifer, and then struggled to keep her job and her place in her family with a wife and two kids. And in Atlanta, a man makes performance art based on his transition from female to male.